A New and Versatile Synthesis of 1,3-Dioxan-5-yl-pyrimidine and Purine Nucleoside Analogues

Antiviral Activity of 5-substituted Pyrimidine Nucleoside Analogues

From a large series of 5—substituted 1—(2—deoxy——D—ribofuranosyl)—ura— cil (dUrd) , 1—(2—deoxy——D—ribofuranosyl)—cytosine (dCyd) and 1—(—D—arabinofurano— syl)—uracil (araU) analogues that have been evaluated for their antiviral proper— ties, the (E)—5—(2—bromovinyl)derivatives emerged as the most potent and most selec— tive antiherpes agents. (E)—5—(2—Bromovinyl)—dUrd (BVDU) and its congeners, ...

Anti‐flavivirus Activity of Different Tritylated Pyrimidine and Purine Nucleoside Analogues

A series of tritylated and dimethoxytritylated analogues of selected pyrimidine and purine nucleosides were synthesized and evaluated for their in vitro inhibitory activity against two important members of the genus Flavivirus in the Flaviviridae family, the yellow fever (YFV) and dengue viruses (DENV). Among all compounds tested, the 5'-O-tritylated and the 5'-O-dimethoxytritylated 5-fluorouri...

Chemical Synthesis of Nucleoside Analogues Chemical Synthesis of Nucleoside Analogues

synthesis and characterization of some new cyclometalated organoplatinum(ii) complexes containing phosphite ligand

در این تحقیق روشی جهت سنتز یک سری از کمپلکس های پلاتین (ii) حاوی لیگاند های دهنده ی فسفری شامل فسفیت و فسفین ارائه شده است. واکنش پیش ماده ی پلاتین (ii)،trans/cis- [ptcl2(sme2)2] ، با 2 اکی مولار از لیگاند p(oph)3در حلال بنزن کمپلکس1، cis-[ptcl2(p(oph)3)2] را تولید می نماید. جهت سنتز کمپلکس سایکلو متال فسفیتی، کمپلکس 1 با 1 اکی والان واکنشگر ptcl2 در حلال زایلن در شرایط رفلاکس زیر گاز آرگون م...

a new algorithm and software of individual life insurance and annuity computation

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